July 24, 2025

Video | Upgraded X-ray laser science: medical applications

After a major upgrade, SLAC's X-ray free-electron laser is 10,000 times brighter and thousands of times faster. Researchers used LCLS to better understand what makes xanthone – a powerful photocatalyst used in cancer therapies – so efficient and how we might control its reactivity. 

close up of instrumentation in the TMO hutch
Video
SLAC is home to the world’s most advanced X-ray laser, and following its recent upgrades, scientists are now able to see how molecules evolve at the smallest, fastest scales imaginable better than ever before. Markus Guehr and his team are looking at xanthone – a powerful, versatile catalyst capable of activating bonds in chemical reactions and even selectively altering DNA. A better understanding of xanthone could lead to medical applications, including innovative cancer therapies. (Olivier Bonin and Sam Soon/SLAC National Accelerator Laboratory)

About SLAC

SLAC National Accelerator Laboratory explores how the universe works at the biggest, smallest and fastest scales and invents powerful tools used by researchers around the globe. As world leaders in ultrafast science and bold explorers of the physics of the universe, we forge new ground in understanding our origins and building a healthier and more sustainable future. Our discovery and innovation help develop new materials and chemical processes and open unprecedented views of the cosmos and life’s most delicate machinery. Building on more than 60 years of visionary research, we help shape the future by advancing areas such as quantum technology, scientific computing and the development of next-generation accelerators.

SLAC is operated by Stanford University for the U.S. Department of Energy’s Office of Science. The Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time.

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