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SLAC has a unique set of tools for looking at viruses, microbes, cells and the tiny machines inside the cell that perform all of life’s functions. This research gives scientists a better understanding of how living things work, what makes us sick and how we can prevent and treat disease. 

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Science of life

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Artist's depiction of a tiny pore in an archaea's crystalline shell
News Brief

Using SSRL, scientists uncovered fossil evidence that the first groups of vertebrates possessed surprisingly advanced eyes. 

fossil specimen in gray rock with bright marcations overlain
News Brief

SLAC scientists develop an approach to better guide the preparation of cell slices for cryogenic-electron tomography imaging.

Cryo-ET image 2
News Brief

Researchers with the Doudna group used SSRL to uncover how viruses use special enzymes to evade a host's defenses. 

A view of SLAC’s Stanford Synchrotron Radiation Lightsource (SSRL), looking west at sunset.
Multimedia

His visit highlighted the breadth of our world-class research and the people and collaborations that make it possible. A key theme of the day...

U.S. Deputy Secretary of Energy Danly watches a simulation of dark matter.
Feature

Oxidizing chemicals break this cellular power plant into useless bits, leading to  Parkinson’s disease, ALS, heart disease, diabetes, cancer and more. A small molecule...

Purple dots arranged in bunches.
News Brief

Cryogenic electron microscopy showed for the first time that large RNA complexes can assemble without the help of proteins. 

Three complex, rainbow-colored molecules of various shapes.
News Brief

The new findings highlight the need for ongoing monitoring of H5N1’s evolution in nature. 

Chickens in a grassy field
News Brief

Researchers found a protein that's essential for an enterovirus to enter human cells. That could help the search for vaccines and treatments. 

A cryo-EM image with blue blobs surrounded by purple lines representing cell nuclei and cell membranes, respectively.
News Brief

Wheat and other sources of gluten can spell trouble for people with the disease, but new findings could aid the development of first-ever drugs...

Close up of wheat in a field.
Feature

Researchers figured out how to spray and freeze a cell sample in its natural state in milliseconds, helping them capture basic biological processes in...

These are two images of the same cell at different times during an experiment.
Feature

Disabling those hinges could be a good strategy for designing vaccines and treatments against a broad range of coronavirus infections.

A 3D image of a round, spiky coronavirus with inset showing how far its spikes can bend.
Feature

Scientists developed a new method to unlock the secrets of RNA. The implications are wide-reaching, from better understanding diseases to designing new therapeutics. 

CXI hutch