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SLAC National Accelerator Laboratory
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    Who we are

    We explore radically new ideas with an entrepreneurial mindset.

    Science and User Support Building to the left and Arrillaga Science Center building to the right from above the Main Quad at SLAC's campus.
    • Research

      Get an overview of research at SLAC: X-ray and ultrafast science, particle and astrophysics, cosmology, particle accelerators, biology, energy and technology.

    • X-ray and Ultrafast science icon X-ray & ultrafast science

      Revealing nature’s fastest processes with X-rays, lasers and electrons

    • Physics of the universe science icon Physics of the universe

      Studying the particles and forces that knit the cosmos together

    • Advanced Accelerators science icon Advanced accelerators

      Building smaller, faster, more powerful accelerators for all

    • Science of life science icon Science of life

      Understanding the machinery of life at its most basic level

    • New technologies science icon New technologies

      Inventing new tools for science and society

    • Energy sciences science icon Energy sciences

      Finding clean, sustainable solutions for the world’s energy challenges

    Spotlight

    SLAC science explained

    Cut through the jargon while exploring our research.

    SAGE campers have fun experimenting with a Van de Graff generator
    • Facilities & Centers

      Learn more about the places where science happens at SLAC: our major facilities, institutes and centers.

    • SCIENTIFIC FACILITIES
      • LCLS website

        Linac Coherent Light Source

      • SSRL website

        Stanford Synchrotron Radiation Lightsource

      • FACET-II website

        Facility for Advanced Accelerator Experimental Tests

      • CryoEM website

        Cryogenic Electron Microscopy

    • JOINT INSTITUTES & CENTERS
      • SIMES website

        Stanford Institute for Materials & Energy Science

      • KIPAC website

        Kavli Institute for Particle Astrophysics & Cosmology

      • PULSE website

        Stanford PULSE Institute

      • SUNCAT website

        Center for Interface Science & Catalysis

      • SLAC-Stanford Battery Center

    NSF-DOE Vera C. Rubin Observatory LSST

    SLAC & Stanford build the world’s largest digital camera for the Legacy Survey of Space and Time (LSST).

    A drone photo of Rubin Observatory while taking pictures during the First Look observing campaign
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      Apply to become a user of our scientific research facilities and instruments.

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      Get the latest news about the lab, our science and discoveries. Explore SLAC events and learn how to participate.

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      This joint publication of SLAC and Fermilab is your view into the world of particle physics.

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    Upcoming public lecture

    Reinventing the way we break down plastic waste

    Thursday, March 26, 2026
    7:00–8:00 p.m. PDT

    Public Lecture: Ozge Bozkurt
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Feature
VIA Stanford News

Stanford single-dose nanoparticle vaccine for COVID-19

Researchers at Stanford are working to develop a single-dose vaccine for SARS-CoV-2 that could potentially be stored at room temperature.

January 5, 2021
The ferritin nanoparticle, shown with red center and six blue spikes.
Feature

SLAC joins the global fight against COVID-19

The lab is responding to the coronavirus crisis by imaging disease-related biomolecules, developing standards for reliable coronavirus testing and enabling other essential research.

April 16, 2020  ·  8 min read
SARS-CoV-2
Feature

SLAC’s new X-ray beamline aids COVID-19 research

Scientists are deploying this state-of-the-art X-ray crystallography facility to study biological molecules related to the COVID-19 pandemic.

August 3, 2020  ·  6 min read
News Brief

In a search for COVID-19 treatments, researchers pursue a drug used on cats

University of Alberta researchers worked with SLAC X-ray scientists to explore the potential of a feline coronavirus drug that may be effective against SARS-CoV-2.

August 27, 2020  ·  2 min read
Feature

Faced with pandemic shortages, researchers combine heat and humidity to disinfect N95 masks for reuse

They found that gently heating N95 masks in high relative humidity could inactivate SARS-CoV-2 virus trapped within the masks, without degrading the masks’ performance.

September 24, 2020  ·  4 min read
Medical workers donning personal protective equipment
Feature

First detailed look at how a molecular Ferris wheel delivers protons to cellular factories

No human cell can function without these tiny machines, which cause disease when they go haywire and offer potential targets for therapeutic drugs.

October 7, 2020  ·  5 min read
Illustration of molecular Ferris wheel moving protons
News Brief

SLAC, Stanford to host national service center for cryo-ET sample preparation

The center complements other NIH centers at SLAC and elsewhere that broaden access to this cutting-edge technology for biomedical research.

November 4, 2020  ·  3 min read
Cryo-EM images of yeast cells with contents highlighted
Past Event
Public lecture

Cryo-EM: Amazing 3D Views of Life’s Molecular Machines

Presented by Wah Chiu. Cryogenic electron microscopy (cryo-EM) is a revolutionary technology for making 3D images of the inner workings of cells in much...

Date Tuesday, September 25, 2018
12:30 p.m.  –  1:30 p.m.  PT
Location Panofsky Auditorium, Science and User Support Building (B53)
stillframe for public lecture
News Brief

Molecular cage gives cryo-EM researchers new insights into a cancer protein

Sandwiching wiggly proteins between two other layers allows scientists to get the most detailed images yet of a protein that’s key to the spread...

February 10, 2022  ·  4 min read
Red molecules are sandwiched between a blue inner shell and purple outer shell.
Feature

Researchers aim X-rays at century-old plant secretions for insight into Aboriginal Australian cultural heritage

By revealing the chemistry of plant secretions, or exudates, these studies build a basis for better understanding and conserving art and tools made with...

May 26, 2022  ·  4 min read
Plant secretion from what is called "grass tree."
News Brief

Resolving a key to enterovirus infection

Researchers found a protein that's essential for an enterovirus to enter human cells. That could help the search for vaccines and treatments. 

April 2, 2025  ·  3 min read
A cryo-EM image with blue blobs surrounded by purple lines representing cell nuclei and cell membranes, respectively.
News Brief

SLAC, Stanford researchers discover large protein-free RNA structures

Cryogenic electron microscopy showed for the first time that large RNA complexes can assemble without the help of proteins. 

May 6, 2025  ·  3 min read
Three complex, rainbow-colored molecules of various shapes.
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