Cells are the basic units of life, but there is nothing basic about them. Observe any cell in a microscope and you will be astounded by the things it can do. For example, immune cells prowl the body to engulf intruders, while bacteria pivot to evade them. To perform these maneuvers, cells are filled with tiny molecular machines. How do these operate? How do they interact? In this lecture, we’ll explore inside cells using advanced microscopy techniques being pioneered at SLAC. We’ll see the interiors of cells in surprising detail, giving clues to cells’ amazing abilities.