X-ray crystallography

Last year's Nobel Prize in Chemistry – shared by Stanford School of Medicine Professor Brian Kobilka and Robert Lefkowitz of Duke University – recognized groundbreaking research in G protein-coupled receptors (GPCRs).

The founding father of DNA nanotechnology – a field that forges tiny geometric building blocks from DNA strands – recently came to SLAC to get a new view of these creations using powerful X-ray laser pulses.

Menlo Park, Calif. — Opening a new window on the way plants generate the oxygen we breathe, researchers used an X-ray laser at the Department of Energy’s (DOE) SLAC National Accelerator Laboratory to simultaneously look at the structure and chemical...

Daniel DePonte, a pioneer in finding ways to serve up a steady and precise supply of crystals, viruses and other precious samples for laser experiments, is the newly hired sample-delivery group leader for SLAC’s Linac Coherent Light Source X-ray laser.

X-rays Pinpoint Drug Target for Bacteria that Affect Hundreds of Millions Worldwide

An international team led by the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory has proved how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes helped to pioneer critical...

Discovery paves the way for new synthesis of antibiotics

Two studies to be published February 3 in Nature demonstrate how the unique capabilities of the world’s first hard X-ray free-electron laser—the Linac Coherent Light Source, located at the Department of Energy’s SLAC National Accelerator Laboratory—could revolutionize the study of...