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What is Cryogenic Electron Microscopy (Cryo-EM)

Cryogenic electron microscopy (cryo-EM) is a revolutionary tool for studying the molecular architecture of protein, viruses, cells and the specialized molecular machines within cells. This video explains how cryo-EM works, from preparing samples for study to capturing atomic imagery and using this imagery to help create treatments for disease.

 

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Olivier Bonin/SLAC National Accelerator Laboratory

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Taking pictures of tiny, flash-frozen things with electrons is revolutionizing biology and technology. SLAC and Stanford host one of the world’s leading facilities for doing cryo-EM research, improving the technology and making it available to researchers across the country.

cryo-EM image of Caulobacter bacterium

Presented by Wah Chiu. Cryogenic electron microscopy (cryo-EM) is a revolutionary technology for making 3D images of the inner workings of cells in much higher resolution than ever possible before.

video still frame from lecture about cryo-EM
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