Topic: Structural molecular biology | SLAC National Accelerator Laboratory

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A tiny change in the length of a chemical bond makes a big difference in the activity of a molecule important in health, drug...

Image - Courtney Krest Roach (SLAC National Accelerator Laboratory)

News Release

A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.

Illustration shows arrestin (yellow), an important type of signaling protein, while docked with rhodopsin (orange).

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An experiment at SLAC’s X-ray laser provides new insight into the ultrafast motions of a muscle protein in a basic biochemical reaction.

Computerized rendering of 3-D structure of myoglobin. The jagged green line represents a pulse of la

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A team led by Stanford University scientists is using software to breathe new life into results from past biological experiments at SLAC’s X-ray laser.

This illustration shows Tiny crystallized biomolecules in a liquid solution (right) are streamed into X-ray laser pulses (shown as a white beam) in this illustration of crystallography at SLAC's Linac Coherent Light Source X-ray laser.

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Developed at SLAC’s LCLS, it could also yield new information from hard-to-study samples in materials science, chemistry and other fields.

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An X-ray laser experiment could lead to new drugs that lessen the side effects caused by powerful painkillers like morphine.

Image - This rendering shows a type of cellular membrane protein known as a delta opioid receptor (purple) with a compound derived from a naturally occurring peptide (orange, blue and red) bound inside its “pocket.” The peptide compound shows promise as a

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Research reveals that the bacterial immune system can better destroy viral attackers by saving genetic records of previously encountered viruses.

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Scientists have assembled an exotic toolbox for experiments that tap into the brightest X-rays on the planet.

Image - This illustration shows a cutaway view of a type of sample system used at the Linac Coherent Light Source X-ray laser that jets samples in a superthin liquid or gel stream into its X-ray pulses. This system is known as a gas dynamic virtual nozzle

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A new experimental station in development at SLAC will expand capabilities for atomic-scale explorations in human health, biology, energy and environmental science.

Image - This artistic rendering shows planned instrumentation for a Macromolecular Femtosecond Crystallography (MFX) experimental station at SLAC's Linac Coherent Light Source. MFX will expand LCLS's capacity and flexibility for biological experiments.

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Discovery at SLAC's Synchrotron Could Lead to New Drug Designs, Treatments

Image - In this rendering, the structure of the nuclear receptor transcription factor Steroidogenic Factor-1 (SF-1, shown in gray) is bound by the signaling phospholipid referred to as "PIP3" (blue and red). (Raymond Blind/UCSF)

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William Weis, PhD, chairman and professor of photon science at the Department of Energy's SLAC National Accelerator Laboratory, has been appointed chairman of the...