Structural molecular biology

With SLAC’s X-ray laser, a research team captured ultrafast changes in fluorescent proteins between “dark” and “light” states. The insights allowed the scientists to design improved markers for biological imaging.

The Scripps researcher is honored for groundbreaking research at the Stanford Synchrotron Radiation Lightsource that accelerated the development of a vaccine for deadly Lassa fever.

Over the next five years they’ll work on getting significantly more information about how catalysts work and improving biological imaging methods.

With SLAC’s X-ray laser and synchrotron, scientists measured exactly how much energy goes into keeping this crucial bond from triggering a cell's death spiral.

The method dramatically reduces the amount of virus material required and allows scientists to get results several times faster.

X-ray studies have produced surprising insights into the workings of a hormone receptor associated with blood pressure regulation that could be a target for new medicines related to cardiovascular conditions, neuropathic pain and tissue growth.

X-rays show details of an insect virus’s crystalline cocoon with sub-nanometer resolution.

Scientists used SLAC's LCLS X-ray laser to make the first snapshots of a chemical interaction between two biomolecules. It changes the shape of millions of molecular switches almost instantaneously, like synchronized swimmers performing the same move.

High-speed X-ray camera reveals ultrafast atomic motions at the root of organisms’ ability to turn light into biological function.

New insights into how bacteria interact with host cells could help fight off harmful microbes.

Scientists have determined in atomic detail how a potential drug molecule fits into and blocks a channel in cell membranes that Ebola and related “filoviruses” need to infect victims’ cells.

Ian Wilson explains how scientists have found a way to induce antibodies to fight a range of influenza viruses, which could some day eliminate the need for seasonal flu shots.