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Tiny microbes and molecular machines have an outsized impact on human health, and they play key roles in the vast global cycles that shape climate and make carbon and nitrogen available to all living things. 

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Science of life

This illustration shows arrestin, an important type of signaling protein

News Feature

Using SLAC's X-ray laser, researchers have for the first time directly observed myoglobin move within quadrillionths of a second after a bond breaks and...

Image - Ilme Schlichting (SLAC National Accelerator Laboratory)
News Feature

Visit the immersive Nobel Labs 360 website about Kobilka, including an interactive tour of his work at SSRL. To find the SSRL section, click...

News Feature

A major international effort at SLAC is focused on improving our views of intact viruses, living bacteria and other tiny samples using the brightest...

Researchers monitor the performance of a single particle imaging experiment
News Feature

Graham George and Ingrid Pickering, a husband and wife X-ray research team, are co-leading a new study in Bangladesh to test whether selenium supplements...

Image - Ingrid Pickering and Graham George, a husband-and-wife X-ray research team, stand next to the controls of SSRL Beam Line 7-3 during a research sabbatical at SLAC. (SLAC National Accelerator Laboratory)
Press Release

A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.

 Illustration shows arrestin (yellow), an important type of signaling protein, while docked with rhodopsin (orange).
Press Release

Scientists for the first time tracked ultrafast structural changes, captured in quadrillionths-of-a-second steps, as ring-shaped gas molecules burst open and unraveled.

Image - This illustration shows shape changes that occur in quadrillionths-of-a-second intervals in a ring-shaped molecule that was broken open by light. (SLAC)
News Feature

An experiment at SLAC’s X-ray laser provides new insight into the ultrafast motions of a muscle protein in a basic biochemical reaction.

Computerized rendering of 3-D structure of myoglobin. The jagged green line represents a pulse of la
News Feature

A team led by Stanford University scientists is using software to breathe new life into results from past biological experiments at SLAC’s X-ray laser.

This illustration shows Tiny crystallized biomolecules in a liquid solution (right) are streamed into X-ray laser pulses (shown as a white beam) in this illustration of crystallography at SLAC's Linac Coherent Light Source X-ray laser.
Press Release

An experiment at SLAC's X-ray laser has revealed in atomic detail how a hypertension drug binds to a cellular receptor that plays a key...

Image - This photo shows a medical device used to monitor blood pressure. In a study at SLAC's Linac Coherent Light Source X-ray laser, researchers studied how a hypertension drug binds to a cellular receptor known as an angiotensin II type 1 receptor.
News Feature

Developed at SLAC’s LCLS, it could also yield new information from hard-to-study samples in materials science, chemistry and other fields.

Image - These charts show (a) the energy profile of two electron bunches that are separated by about 6 picoseconds, which are later stimulated to emit (b) two X-ray pulses separated by femtoseconds.
News Feature

For the first time, researchers have produced a 3-D image revealing some of the inner structure of an intact, infectious virus.

Image - This rendering shows a 3-D reconstruction of a Mimivirus, based on an analysis of a collection of X-ray diffraction patterns obtained in an experiment at SLAC's Linac Coherent Light Source X-ray laser. (Uppsala University)
News Feature

An X-ray laser experiment could lead to new drugs that lessen the side effects caused by powerful painkillers like morphine.

Image - This rendering shows a type of cellular membrane protein known as a delta opioid receptor (purple) with a compound derived from a naturally occurring peptide (orange, blue and red) bound inside its “pocket.” The peptide compound shows promise as a