The universe is home to numerous exotic and beautiful phenomena, some of which can generate almost inconceivable amounts of energy. While the night sky appears calm, it is populated by colossal explosions, jets from supermassive black holes, rapidly rotating neutron stars, and shock waves of gas moving at supersonic speeds. These accelerators in the sky boost particles to energies far beyond those we can produce on earth. New types of telescopes, including the Fermi Gamma-ray Space Telescope orbiting in space, are now discovering a host of new and more powerful accelerators. Please come and see how these observations are revising our picture of the most energetic phenomena in the universe.