SLAC National Accelerator Laboratory is responding to the coronavirus crisis by imaging disease-related biomolecules, developing standards for reliable coronavirus testing and enabling other essential research. As the world grapples with COVID-19, SLAC scientists are turning their attention to SARS-CoV-2, the virus behind the disease. The studies described in this video do not use infectious materials, such as live viruses.
as the world grapples with kovat 19
slack scientists are turning their
attention to SARS Kobe - the virus
behind the disease one thing they'd like
to know is the detailed structure of key
parts of the virus that could help
chemists design drugs that stop the
virus from infecting and hijacking
ourselves with slacks cryo-electron
microscopy scientists freeze bits of a
virus in place then fire electrons at
them to look at their atomic structures
and how those structures bend and twist
they can even look at an entire frozen
virus or cell which can reveal details
of how viruses infect cells and what
they do once inside at the Stanford
synchrotron radiation light source s srl
researchers shoot powerful x-ray beams
at proteins and other molecules
extracted from the virus to reveal their
atomic structure and see how their
shapes change as they bind to other
molecules for example these techniques
can help determine the shape of the
corona virus spike proteins that attach
to our cells and how to modify them to
prevent infection similar studies at
SLAC have contributed to our
understanding of viruses behind past
epidemics such as the original SARS
coronavirus and the Zika virus
slack's staff and other scientists who
use our facilities are only just
beginning their research on Tsarskoe be
too much of the work will be done
remotely with the help of automated
systems it will take many scientists at
organizations all over the globe to
fight Co vid 19 we are proud to be
joining them and look forward to
contributing to the world's
understanding of this deadly disease
Olivier Bonin/SLAC National Accelerator Laboratory
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SLAC is a vibrant multiprogram laboratory that explores how the universe works at the biggest, smallest and fastest scales and invents powerful tools used by scientists around the globe. With research spanning particle physics, astrophysics and cosmology, materials, chemistry, bio- and energy sciences and scientific computing, we help solve real-world problems and advance the interests of the nation.
SLAC is operated by Stanford University for the U.S. Department of Energy’s Office of Science. The Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time.
This graphic illustration shows how a SARS-CoV-2 protease attaches to a new molecule. The new molecule is meant to slow the virus inside an...
This image shows the SARS-CoV-2 virus's main protease, Mpro, and two strands of a human protein, called NEMO.
This graphic illustration shows how a SARS-CoV-2 protease attaches to a new molecule. The new molecule is meant to slow the virus inside an...
This image shows the SARS-CoV-2 virus's main protease, Mpro, and two strands of a human protein, called NEMO.
