X-ray Crystallography

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January 28, 2015
News Feature
Research performed in part at SLAC has provided new insights into how "TH proteins" couple two important processes needed to maintain healthy cells.
December 11, 2014
News Feature
A scientist at Germany’s DESY lab who participated in pioneering studies at SLAC's LCLS has been awarded a scientific prize by a research foundation.
Image - Henry Chapman (DESY)
December 4, 2014
News Feature
Researchers captured the highest-resolution snapshots ever taken with an X-ray laser that show changes in a protein’s structure over time.
Image - This illustration depicts an experiment at SLAC that revealed how a protein from photosynthetic bacteria changes shape in response to light.
November 21, 2014
News Feature
Scientists at the Department of Energy’s SLAC National Accelerator Laboratory are combining the speed and precision of robots with one of the brightest X-ray lasers on the planet for pioneering studies of proteins important to biology and drug discovery.
This illustration shows the components in an experimental setup used in crystallography experiments at SLAC's Linac Coherent Light Source X-ray laser.
November 13, 2014
News Feature
A new experimental station in development at SLAC will expand capabilities for atomic-scale explorations in human health, biology, energy and environmental science.
Image - This artistic rendering shows planned instrumentation for a Macromolecular Femtosecond Crystallography (MFX) experimental station at SLAC's Linac Coherent Light Source. MFX will expand LCLS's capacity and flexibility for biological experiments.
October 6, 2014
News Feature
Researchers have discovered that some common messenger molecules in human cells double as hormones when joined to a protein that interacts with DNA.
Image - In this rendering, the structure of the nuclear receptor transcription factor Steroidogenic Factor-1 (SF-1, shown in gray) is bound by the signaling phospholipid referred to as "PIP3" (blue and red). (Raymond Blind/UCSF)
September 22, 2014
News Feature
SSRL protein crystallography expert joined research effort that could lead to a safe and effective alternative to chemotherapy.
September 3, 2014
News Feature
Scientists have for the first time mapped the atomic structure of a protein within a living cell. The technique, which peered into cells with an X-ray laser, could allow scientists to explore some components of living cells as never before.
Image - These micrograph images show rod-shaped bacterial cells suspended in pure water. The dark rectangular shapes inside the cells correspond to naturally occurring crystals within the cells.
June 12, 2014
News Feature
Even in their infancy, X-ray lasers such as SLAC's Linac Coherent Light Source are notching a list of important discoveries, and a special issue of a scientific journal highlights their unique contributions to biological sciences.
Image - This illustration represents data derived from 175,000 X-ray diffraction patterns of Trapanosoma brucei cathepsin B, a protein relevant to African sleeping sickness, measured with X-ray pulses at SLAC's Linac Coherent Light Source. (CFEL)
May 22, 2014
Press Release
By finding surprising similarities in the way immune system defenders bind to disease-causing invaders, a new study may help scientists develop new treatments.
Conceptual art - see caption

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