X-ray Crystallography

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X-ray Laser Brings Cellular Messengers into Focus

Last year's Nobel Prize in Chemistry – shared by Stanford School of Medicine Professor Brian Kobilka and Robert Lefkowitz of Duke University – recognized groundbreaking research in G protein-coupled receptors (GPCRs). GPCRs are embedded in cell membranes. They interact with signaling molecules outside of cells and trigger responses within cells.

X-ray Laser Explores New Uses for DNA Building Blocks

The founding father of DNA nanotechnology – a field that forges tiny geometric building blocks from DNA strands – recently came to SLAC to get a new view of these creations using powerful X-ray laser pulses.

For decades, Nadrian C. "Ned" Seeman, a chemistry professor at New York University, has studied ways to assemble DNA strands into geometric shapes and 3-D crystals with applications in biology, biocomputing and nanorobotics.

X-ray Laser Sees Photosynthesis in Action

Menlo Park, Calif. — Opening a new window on the way plants generate the oxygen we breathe, researchers used an X-ray laser at the Department of Energy’s (DOE) SLAC National Accelerator Laboratory to simultaneously look at the structure and chemical behavior of a natural catalyst involved in photosynthesis for the first time.

X-ray Laser Probes Biomolecules to Individual Atoms

An international team led by the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory has proved how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes helped to pioneer critical new investigative avenues in biology.

Giant Virus, Tiny Protein Crystals Show X-ray Laser's Power and Potential

Two studies to be published February 3 in Nature demonstrate how the unique capabilities of the world’s first hard X-ray free-electron laser—the Linac Coherent Light Source, located at the Department of Energy’s SLAC National Accelerator Laboratory—could revolutionize the study of life.

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