X-ray Crystallography

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July 22, 2015
Press Release
Long-sought Discovery Fills in Missing Details of Cell 'Switchboard'
A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.
May 1, 2015
News Feature
New Tool Shrinks Big Data in Biology Studies at SLAC's X-ray Laser
A team led by Stanford University scientists is using software to breathe new life into results from past biological experiments at SLAC’s X-ray laser.
This illustration shows Tiny crystallized biomolecules in a liquid solution (right) are streamed into X-ray laser pulses (shown as a white beam) in this illustration of crystallography at SLAC's Linac Coherent Light Source X-ray laser.
April 23, 2015
Press Release
X-ray Study May Aid in Designing Better Blood Pressure Drugs
An experiment at SLAC's X-ray laser has revealed in atomic detail how a hypertension drug binds to a cellular receptor that plays a key role in regulating blood pressure.
Image - This photo shows a medical device used to monitor blood pressure. In a study at SLAC's Linac Coherent Light Source X-ray laser, researchers studied how a hypertension drug binds to a cellular receptor known as an angiotensin II type 1 receptor.
March 10, 2015
News Feature
New 2-Color X-ray Laser Technique Could Reveal Atomic Detail of Medically Important Proteins
Developed at SLAC’s LCLS, it could also yield new information from hard-to-study samples in materials science, chemistry and other fields.
Image - These charts show (a) the energy profile of two electron bunches that are separated by about 6 picoseconds, which are later stimulated to emit (b) two X-ray pulses separated by femtoseconds.
February 17, 2015
News Feature
Study Could Pave the Way for Painkillers with Fewer Side Effects
An X-ray laser experiment could lead to new drugs that lessen the side effects caused by powerful painkillers like morphine.
Image - This rendering shows a type of cellular membrane protein known as a delta opioid receptor (purple) with a compound derived from a naturally occurring peptide (orange, blue and red) bound inside its “pocket.” The peptide compound shows promise as a
February 3, 2015
News Feature
Record Keeping Helps Bacteria’s Immune System Fight Invaders
Research reveals that the bacterial immune system can better destroy viral attackers by saving genetic records of previously encountered viruses.
February 2, 2015
News Feature
5 Ways to Put Tiny Targets in Front of an X-ray Laser
Scientists have assembled an exotic toolbox for experiments that tap into the brightest X-rays on the planet.
Image - This illustration shows a cutaway view of a type of sample system used at the Linac Coherent Light Source X-ray laser that jets samples in a superthin liquid or gel stream into its X-ray pulses. This system is known as a gas dynamic virtual nozzle
January 28, 2015
News Feature
X-ray Study Reveals Division of Labor in Cell Health Protein
Research performed in part at SLAC has provided new insights into how "TH proteins" couple two important processes needed to maintain healthy cells.
December 11, 2014
News Feature
DESY's Henry Chapman Awarded Leibniz Prize for X-ray Laser Research
A scientist at Germany’s DESY lab who participated in pioneering studies at SLAC's LCLS has been awarded a scientific prize by a research foundation.
Image - Henry Chapman (DESY)
December 4, 2014
News Feature
X-ray Laser Reveals How Bacterial Protein Morphs in Response to Light
Researchers captured the highest-resolution snapshots ever taken with an X-ray laser that show changes in a protein’s structure over time.
Image - This illustration depicts an experiment at SLAC that revealed how a protein from photosynthetic bacteria changes shape in response to light.

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