With SLAC’s X-ray laser, a research team captured ultrafast changes in fluorescent proteins between “dark” and “light” states. The insights allowed the scientists to design improved markers for biological imaging.
X-ray studies have produced surprising insights into the workings of a hormone receptor associated with blood pressure regulation that could be a target for new medicines related to cardiovascular conditions, neuropathic pain and tissue growth.
Scientists used SLAC's LCLS X-ray laser to make the first snapshots of a chemical interaction between two biomolecules. It changes the shape of millions of molecular switches almost instantaneously, like synchronized swimmers performing the same move.
A new study with the LCLS X-ray laser could change the way researchers take atomic-level snapshots of important biological machineries, potentially affecting research in drug development, clean energy production and many more areas.